ted. Added file 10. Enriched terms in up-regulated genes among Supplemented Infected vs Control Infected. Further file 11. Enriched terms inside the list of differentially upregulated genes among the groups Manage Infected vs Supplemented Infected. Further file 12. Typical liveweight and age (typical deviation) for each group in the beginning and finish of your experiment. Additional file 13. Composition in the TLR3 Storage & Stability handle protein and supplemented protein diets. Additional file 14. Bromatological composition (g kg-1 of dry matter at one hundred ) and energy (MJ) on the diets’ ingredients. Additional file 15. Bromatological analysis with the diet. Additional file 16. List of ovarian RNA samples, their concentration, 260/280 and 260/230 absorbance ratios. Extra file 17. EM estimation algorithm procedure. Added file 18. Statistical methodology made use of inside the Enrichment evaluation. More file 19. Protein Network analysis. Acknowledgements Not applicable. Arrive recommendations statement This study was carried out in compliance with all the ARRIVE guidelines. Authors’ contributions P.S.H. performed the in vivo and laboratory experiments, analysed the information and wrote the manuscript. C.M.S.C. carried out the in vivo and laboratory experiments. R.C.L. performed the statistical analyses, assisted with manuscript writing and revision. D.G.C. helped with qPCR arranging and qPCR information evaluation. L.M.K. cultivated and provided the Haemonchus contortus larvae. S.M.T. assisted within the preparing of experiments. H. L. elaborated the study design and arranging, assisted inside the manuscript revision. The author(s) read and authorized the final manuscript. Author’s information and facts Paula Suarez-Henriques is a veterinary surgeon with a Master in Animal Science and also a Doctorate in Animal Science. She obtained each degrees within the last six years in the University of S Paulo in Brazil. In July 2020, she presented part of her doctorate study in the Society for the Study of Reproduction virtual meeting. Prior to that, she worked as a veterinarian clinician in addition to a study assistant in laboratories studying molecular pathology of δ Opioid Receptor/DOR web breast cancers, cell and molecular biology in mammary gland improvement, and numerous myeloma resistance to alkylating agents. Funding We thank the National Council for Scientific and Technological Analysis -(CNPq – Brazil) and CAPES for the economic help with Paula SuarezHenriques’ PhD studentship bursary number 141846/2017 and, for funding the charges of reagents and equipment vital for the accomplishment of this research project, with procedure numbers CNPq 311008/2016-0 and CNPq 420373/2016. We also thank S Paulo Research Assistance FoundationSupplementary InformationThe on the net version contains supplementary material accessible at doi. org/10.1186/s12917-021-03020-7. Extra file 1: Table S1. RNA sequencing data high-quality summary. Added file 2: Table S2. Number of sequences and Sequencing depth generated by RNA sequencing.Suarez-Henriques et al. BMC Veterinary Research(2021) 17:Page 22 of(FAPESP) method numbers 2017/50451 and 2017/18086-0, for added funding for reagents. Availability of data and materials The datasets made use of and/or analysed through the existing study are available inside the More files. The files that are not in this section may perhaps be offered under affordable request to Dr. Helder Louvandini e-mail address: [email protected] approval This research project, with its protocol and procedures employed, have been eth