Product Name :
Rabbit anti-S1PR1 Polyclonal Antibody
Synonym :
CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1
Host :
Rabbit
Species Reactivity:
Human, Mouse
Specificity :
Predicted Reactivity:
Applications :
WB 1:500 – 1:2000
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 303-382 of human S1PR1 (NP_001391.2).
Concentration :
Purification :
Affinity purification
Clonality:
Polyclonal Antibody
Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles
Research areas :
Background :
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
UniProt :
P21453
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1 |Host Rabbit |Species Reactivity Human, Mouse |Applications WB 1:500 – 1:2000 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 303-382 of human S1PR1 (NP_001391.2). |Positive control NIH/3T3,SH-SY5Y,Mouse kidney |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. |Cellular localization Cell membrane,Endosome,Membrane raft,Multi-pass membrane protein |UniProt P21453 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-S1PR1 Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
2563892-44-2 Data Sheet 2353-33-5 supplier PMID:30000594 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com