Ochs that met compliance targets all round and by group. Because our sample size was not adequate to account for the correlation of CPR epochs inside events, epoch-level percentages are reported for descriptive purposes only. For the principal statistical analysis, we calculated a single summary per occasion because the percentage of epochs with outstanding CPR (main outcome) and compliant for each excellent target individually (secondary outcomes). Percent of compliant epochs was compared across AVF vs. NoAVF groups utilizing Wilcoxon rank-sum tests. Statistical analysis was completed applying Stata (Version 12.0, StataCorp, College Station, TX).NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptResuscitation. Author manuscript; readily available in PMC 2015 January 01.Sutton et al.PageResultsBetween November 2011 and May 2013, 15 PICU cardiac arrests in kids 1 to eight years of age occurred at our institution, of which 8 (53 ) had CPR recording defibrillators deployed in the course of the resuscitation attempt: four events in the No Audiovisual Feedback (NoAVF) group (IDE device) and 4 events inside the Audiovisual Feedback (AVF) group (“offlabel” use of typical Heartstart MRx with Q-CPR option) (Figure 1). These events resulted in 285 thirty-second epochs of CPR (152 NAVF; 133 AVF). A total of 15,960 CCs have been offered for evaluation. Table 1 includes topic and occasion demographics for the all round cohort and for the two feedback groups. Measured characteristics didn’t differ among the two feedback groups. For the overall cohort in the event level, median price was 115 (IQR 111, 121) CC/min, median CCF was 0.94 (IQR 0.91, 0.98), median percentage of CC with leaning was 7.0 (IQR three.5, 10.9) , and typical CC depth was 45 8 mm. Event level summary statistics for the two feedback groups had been: AVF- median rate was 111 (IQR 108, 115) CC/min, median CCF was 0.94 (0.91, 0.97), median percentage of CC with leaning was 7.0 (IQR three.1, eight.Thiamine nitrate two) , and average CC depth was 48 4 mm; NoAVF- median rate was 121 (IQR 115, 137) CC/ min, median CCF was 0.95 (0.80, 0.98), median percentage of CC with leaning was 9.7 (IQR three.5, 35.five) , and typical CC depth was 42 11 mm. Force measurements and mattress compensated CC depths (i.e., actual chest deflection through chest compression) were readily available for IDE device events only. Force measurements were: median peak force was 29.Polydatin 7 (IQR 25.9, 34.6) kg; median residual leaning force was 1.96 (IQR 1.2, 3.PMID:23771862 3) kg. The average mattress compensated CC depth19 was: 28 6mm. General, percentage of epochs reaching compliance targets was 54 (153 / 285) for price, 19 (54 / 285) for depth, 88 (250 / 285) for CCF, 79 (226 / 285) for leaning, and 8 (24 / 285) for great CPR (Figure 2). The percentage of epochs meeting compliance targets within the AVF group in comparison to NoAVF was for price (80 vs. 31 ), depth (24 vs. 14 ), CCF (90 vs. 86 ), leaning (95 vs. 65 ), and excellent CPR (17 vs. 1 ) (Figure three). The median percentage of epochs per occasion reaching Guidelines increased with AVF compared to NoAVF for price [88 (IQR: 79, 94) vs. 39 (IQR 18, 62) ; p=0.043] and fantastic CPR [28 (IQR: 7.2, 52) vs. 0 (IQR: 0, 1) ; p=0.018]. Of note, the distinction in between AVF and NoAVF for price was driven mainly by the avoidance of excessively rapidly CC prices ( 120 CC/min): 9.five (IQR: 2.9, 19.three) vs. 55 (IQR: 32, 81) ; p=0.043).NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptDiscussionTo our know-how, that is the first study to repo.