Isoflurane
Product: JK184
Identifier : DBSNPE000350
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Voltage-dependent L-type calcium channel subunit alpha-1S
Gene Name : CACNA1S
UniProt ID : Q13698
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 22209345
Isoflurane
Product: Ensartinib
Identifier : DBSNPE000351
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Voltage-dependent L-type calcium channel subunit alpha-1S
Gene Name : CACNA1S
UniProt ID : Q13698
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 22908233
Isoflurane
Product: Dehydroisoandrosterone 3-acetate
Identifier : DBSNPE000352
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21536586
Isoflurane
Product: Pemafibrate
Identifier : DBSNPE000353
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21182085
Isoflurane
Product: PF06650833
Identifier : DBSNPE000354
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21518785
Isoflurane
Product: Erythromycin Cyclocarbonate
Identifier : DBSNPE000355
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21356374
Isoflurane
Product: E7820
Identifier : DBSNPE000356
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21492444
Isoflurane
Product: BX517
Identifier : DBSNPE000357
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21803942
Isoflurane
Product: Leonurine
Identifier : DBSNPE000358
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21533185
Isoflurane
Product: Ketanserin (tartrate)
Identifier : DBSNPE000359
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 21818323
Isoflurane
Product: Rotenone
Identifier : DBSNPE000360
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 20733032
Isoflurane
Product: BAPTA
Identifier : DBSNPE000361
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 20448060
Isoflurane
Product: AM-2394
Identifier : DBSNPE000362
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 20696772
Isoflurane
Product: GSK2256098
Identifier : DBSNPE000363
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 19897485
Isoflurane
Product: RAF709
Identifier : DBSNPE000364
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 19008331
Isoflurane
Product: VU0364770
Identifier : DBSNPE000365
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18950659
Isoflurane
Product: Rbin-1
Identifier : DBSNPE000366
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 19477925
Isoflurane
Product: Piperoxan (hydrochloride)
Identifier : DBSNPE000367
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 19211805
Isoflurane
Product: Leonurine (hydrochloride)
Identifier : DBSNPE000368
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18974111
Isoflurane
Product: Impurity of Doxercalciferol
Identifier : DBSNPE000369
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18317592
Isoflurane
Product: Dehydrocorydaline (chloride)
Identifier : DBSNPE000370
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18177995
Isoflurane
Product: Epiberberine (chloride)
Identifier : DBSNPE000371
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18354059
Isoflurane
Product: Menadione bisulfite (sodium)
Identifier : DBSNPE000372
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18505969
Isoflurane
Product: L-Ascorbic acid (sodium)
Identifier : DBSNPE000373
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18339713
Isoflurane
Product: ARS-853
Identifier : DBSNPE000374
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18566133
Isoflurane
Product: Monepantel
Identifier : DBSNPE000375
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18644836
Isoflurane
Product: Ketanserin
Identifier : DBSNPE000376
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 18310301
Isoflurane
Product: (R)-Flurbiprofen
Identifier : DBSNPE000377
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 17320868
Isoflurane
Product: JPH203
Identifier : DBSNPE000378
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 17272673
Isoflurane
Product: ASK1-IN-1
Identifier : DBSNPE000379
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 17493623
Isoflurane
Product: URB602
Identifier : DBSNPE000380
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 17785421
Isoflurane
Product: NSC23005 (sodium)
Identifier : DBSNPE000381
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14387A>G (rs118192167 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 17332286
Isoflurane
Product: Sophoflavescenol
Identifier : DBSNPE000382
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14477C>T (rs121918595 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 16627587
Isoflurane
Product: Phorbol
Identifier : DBSNPE000383
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 17062671
Isoflurane
Product: Epoxymicheliolide
Identifier : DBSNPE000384
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14512C>G (rs193922878 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 16965620
Isoflurane
Product: Protodioscin
Identifier : DBSNPE000385
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 16223864
Isoflurane
Product: Hederacoside D
Identifier : DBSNPE000386
Drug : DB00753 (Isoflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14693T>C (rs118192170 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Forane® (isoflurane, USP) [package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2010. [Link]
PMID: 16007178