Desflurane
Product: Tanshinone IIA
Identifier : DBSNPE000313
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Voltage-dependent L-type calcium channel subunit alpha-1S
Gene Name : CACNA1S
UniProt ID : Q13698
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 3756133
Desflurane
Product: Nuciferine
Identifier : DBSNPE000314
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Voltage-dependent L-type calcium channel subunit alpha-1S
Gene Name : CACNA1S
UniProt ID : Q13698
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 3778949
Desflurane
Product: Chrysophanol
Identifier : DBSNPE000315
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24658113
Desflurane
Product: Dihydrotanshinone I
Identifier : DBSNPE000316
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 22489865
Desflurane
Product: Astragaloside IV
Identifier : DBSNPE000317
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 22398409
Desflurane
Product: SF1670
Identifier : DBSNPE000318
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 20803239
Desflurane
Product: Scutellarin
Identifier : DBSNPE000319
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 19596275
Desflurane
Product: Tanshinone IIA sulfonate (sodium)
Identifier : DBSNPE000320
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 12943986
Desflurane
Product: GS-7340 (hemifumarate)
Identifier : DBSNPE000321
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 12890703
Desflurane
Product: Podocarpic acid
Identifier : DBSNPE000322
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 11708925
Desflurane
Product: IDE1
Identifier : DBSNPE000323
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 26397183
Desflurane
Product: SYP-5
Identifier : DBSNPE000324
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 26453052
Desflurane
Product: IPI549
Identifier : DBSNPE000325
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 25723814
Desflurane
Product: Antibiotic-5d
Identifier : DBSNPE000326
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 25874233
Desflurane
Product: KRIBB11
Identifier : DBSNPE000327
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 25549949
Desflurane
Product: MX69
Identifier : DBSNPE000328
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 25730107
Desflurane
Product: Conduritol B epoxide
Identifier : DBSNPE000329
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 25663821
Desflurane
Product: BBT594
Identifier : DBSNPE000330
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 25000562
Desflurane
Product: GGTI298
Identifier : DBSNPE000331
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24877132
Desflurane
Product: UNC3866
Identifier : DBSNPE000332
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24621993
Desflurane
Product: MRE-269
Identifier : DBSNPE000333
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24334513
Desflurane
Product: N-Desmethylclozapine
Identifier : DBSNPE000334
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24613724
Desflurane
Product: AS1517499
Identifier : DBSNPE000335
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24670778
Desflurane
Product: DREADD agonist 21
Identifier : DBSNPE000336
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 26417324
Desflurane
Product: ONO-7300243
Identifier : DBSNPE000337
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24048848
Desflurane
Product: DG051
Identifier : DBSNPE000338
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24222765
Desflurane
Product: Oleanolic acid derivative 1
Identifier : DBSNPE000339
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 23756706
Desflurane
Product: Oleanolic acid derivative 2
Identifier : DBSNPE000340
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24191028
Desflurane
Product: Protocatechuic acid
Identifier : DBSNPE000341
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 23804112
Desflurane
Product: PF-06282999
Identifier : DBSNPE000342
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 23718638
Desflurane
Product: L-Praziquanamine
Identifier : DBSNPE000343
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 21884022
Desflurane
Product: CA-074 methyl ester
Identifier : DBSNPE000344
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14387A>G (rs118192167 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 24068106
Desflurane
Product: Nicainoprol
Identifier : DBSNPE000345
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14477C>T (rs121918595 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 22142990
Desflurane
Product: HT-2157
Identifier : DBSNPE000346
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 22810004
Desflurane
Product: Niraparib metabolite M1
Identifier : DBSNPE000347
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14512C>G (rs193922878 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 22509330
Desflurane
Product: PF-1355
Identifier : DBSNPE000348
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 22896656
Desflurane
Product: ML RR-S2 CDA (ammonium salt)
Identifier : DBSNPE000349
Drug : DB01189 (Desflurane)
Interacting Gene/Enzyme : Ryanodine receptor 1
Gene Name : RYR1
UniProt ID : P21817
Defining Change(s) :
- c.14693T>C (rs118192170 )
Allele Name : Not Available
Genotype(s) : Not Available
Type(s) : ADR Inferred
Groups : Malignant hyperthermia vulnerability
Description : Malignant hyperthermia.
References :
- Suprane® (desflurane, USP) liquid[package insert]. Deerfield, Illinois: Baxter Healthcare Corporation; 2016. [Link]
PMID: 23071688